Gas-phase infrared spectrum and acidity of the radical cation of 9-methylguanine.
نویسندگان
چکیده
Oxidative damage to DNA yields guanine radical cations. Their gas-phase IR spectroscopic signature and acidity have been modelled by the radical cation of 9-methylguanine. Comparisons with quantum chemistry calculations suggest that radical cation formation produces the ground-state keto tautomer, which has an N-H acidity enhanced by ~470 kJ mol(-1).
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 66 شماره
صفحات -
تاریخ انتشار 2013